Search on: JNK MITOGEN-ACTIVATED PROTEIN KINASES 
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Descriptor English:   JNK Mitogen-Activated Protein Kinases 
Descriptor Spanish:   Proteínas Quinasas Activadas por JNK Mitógeno 
Descriptor Portuguese:   Proteínas Quinases JNK Ativadas por Mitógeno 
Tree Number:   D08.811.913.696.620.682.700.567.513
D08.811.913.696.620.682.700.646.750.374
D12.644.360.450.340
D12.776.476.450.340
Definition English:   A subgroup of mitogen-activated protein kinases that activate TRANSCRIPTION FACTOR AP-1 via the phosphorylation of C-JUN PROTEINS. They are components of intracellular signaling pathways that regulate CELL PROLIFERATION; APOPTOSIS; and CELL DIFFERENTIATION. 
Indexing Annotation English:   note specifics
History Note English:   2005 
Allowable Qualifiers English:  
administration & dosage adverse effects
antagonists & inhibitors analysis
biosynthesis blood
cerebrospinal fluid chemistry
classification chemical synthesis
contraindications drug effects
deficiency diagnostic use
economics genetics
history immunology
isolation & purification metabolism
pharmacology physiology
pharmacokinetics poisoning
radiation effects supply & distribution
secretion standards
toxicity therapeutic use
ultrastructure urine
Record Number:   38731 
Unique Identifier:   D048031 

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